Circulating human papillomavirus (HPV) DNA for surveillance of HPV-related oropharyngeal squamous cell carcinoma (HPV-OPSCC)

Townsville Hospital and Health Service
Ulf Schmitz
Role

Chief Investigator

Description

We hypothesize that cHPV-DNA-based post-treatment surveillance via capture-based NGS would have excellent negative predictive value (NPV) and positive predictive value (PPV) similar or superior to PCR-based testing in patients with HPV-OPSCC, leading to improvement in outcome prediction. We also hypothesize that cHPV-DNA-based surveillance is more cost-effective compared with standard routine clinical follow-up.

Date

01 Aug 2024 - 31 Jul 2026

Project Type

GRANT

Keywords

N/A

Funding Body

Townsville Hospital and Health Service

Amount

49498

Project Team

N/A