Characterisation of avian circovirus protein complexes: A crucial step in tackling fatal viral infection in birds
Role
Principal Investigator
Description
This project aims to better understand how the beak and feather disease virus (BFDV) is assembled. The virus affects Australian native birds, which are currently endangered or critically endangered and has the potential to disrupt native ecosystems. By using interdisciplinary research, this project will generate fundamental knowledge by which BFDV protein complexes are formed. The intended outcomes of the project include the identification of key binding interfaces involved in viral formation processes. This information intends to guide cost-effective delivery of potential anti-viral options or vaccines for endangered Australian native parrots, and for use as a model to target other pathogenic DNA viruses of interest.
Date
13 Jan 2020 - 31 Dec 2024
Project Type
GRANT
Keywords
virology, structural virology, virus-host interaction
Funding Body
Australian Research Council
Amount
37427
Project Team
Subir Sarker