Age-associated properties of intraepithelial lymphocytes, and their relation to intestinal diseases (Old ID 27181)

National Health and Medical Research Council (NHMRC)
Roland Ruscher
Role

Principal Investigator

Description

Inflammatory bowel disease (IBD) and colorectal cancer are a severe burden to those affected. While the peak onset age of IBD lies in early adulthood, colorectal cancer predominantly affects people over 50 years of age. How gut immunity fails in the context of age is poorly understood. This program will establish cornerstones of the intestinal immune system over different stages in life, and thereby help to design better treatment strategies that are adjusted to an individual’s age.

Date

01 Jan 2022 - 31 Dec 2026

Project Type

FELLOWSHIP

Keywords

IBD;IEL;T Cells;Colitis;Mucosal Immunology;Colorectal cancer

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

600740

Project Team

N/A