Role of liver fluke granulin in cholangiocarcinogenesis (Old ID 19534)

National Institute of Health
Alex Loukas
Role

Principal Investigator

Description

Long term infection with liver fluke - a food-borne parasitic worm -leads to cholangiocarcinoma (CCA), a form of liver cancer with a dismal prognosis. Previously we identified a protein from these parasites that may cause this cancer. This new project will investigate the role of this parasite protein (termed granulin) in cancer, which may lead to new treatments and control for fluke infection and CCA.

Date

01 Jan 2012 - 31 Jul 2018

Project Type

GRANT

Keywords

Cancer;Biomarkers;Opisthorchis viverrine;Cholangiocarcinoma;Infection-induced carcinoma;Proteomics

Funding Body

National Institute of Health

Amount

658669

Project Team

Jason Mulvenna