Investigating post-transcriptional gene regulation in cancer (Old ID 27328)

National Health and Medical Research Council (NHMRC)
Role

Principal Investigator

Description

In this project we willl employ integrative systems medicine approaches to generate a detailed mechanistic overview of multi-level cancer gene regulation and provide novel avenues for the treatment of aggressive tumours. We will determine patterns of gene regulation in leukaemia and test whether these patterns are predictive for disease outcome. We will devise strategies for the therapeutic interference with gene regulation to effectively sensitise aggressive tumours to chemotherapy and thereby diminish tumour cell populations and prevent relapse.

Date

12 Jul 2021 - 31 Dec 2025

Project Type

FELLOWSHIP

Keywords

Bioinformatics;Breast Cancer;Gene Regulation;Computational Biology;Leukaemia;RNA biology

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

577910.2

Project Team

N/A