Investigating post-transcriptional gene regulation in cancer (Old ID 27328)
Role
Principal Investigator
Description
In this project we willl employ integrative systems medicine approaches to generate a detailed mechanistic overview of multi-level cancer gene regulation and provide novel avenues for the treatment of aggressive tumours. We will determine patterns of gene regulation in leukaemia and test whether these patterns are predictive for disease outcome. We will devise strategies for the therapeutic interference with gene regulation to effectively sensitise aggressive tumours to chemotherapy and thereby diminish tumour cell populations and prevent relapse.
Date
12 Jul 2021 - 31 Dec 2025
Project Type
FELLOWSHIP
Keywords
Bioinformatics;Breast Cancer;Gene Regulation;Computational Biology;Leukaemia;RNA biology
Funding Body
National Health and Medical Research Council (NHMRC)
Amount
577910.2
Project Team
N/A