Deciphering the immune mechanisms of novel TB vaccine candidates in preclinical models of active disease and latent Mycobacterium tuberculosis infection (Old ID 27399)

National Institute of Health
Andreas Kupz
Role

Principal Investigator

Description

Tuberculosis kills more people than any other infectious disease, and approximately one third of the world's population is latently infected with Mycobacterium tuberculosis. New vaccines are needed. These vaccines should be safe and effective against various forms of tuberculosis. This project aims to combine a new mouse model of latent tuberculosis with distinct rabbit models of TB to develop and test new vaccines against TB.

Date

17 Jun 2021 - 31 May 2025

Project Type

GRANT

Keywords

Mycobacterium Tuberculosis;Bcg;Vaccine Development;Immunology;Infectious disease

Funding Body

National Institute of Health

Amount

448427.73

Project Team

N/A