New strategies for improved tuberculosis vaccines (Old ID 22533)

National Health and Medical Research Council (NHMRC)
Andreas Kupz
Role

Principal Investigator

Description

Tuberculosis is one of the most threatening infectious diseases worldwide due to the low efficiency of the only licensed anti-tuberculosis vaccine, BCG. This project aims to interrogate two previously neglected immune mechanisms and their potential to enhance vaccine-induced immunity by incorporating these mechanisms into new genetically modified BCG strains. We will also investigate alternative BCG vaccination routes to generate long-lived immune cells that can rapidly control the infection.

Date

01 Jan 2017 - 31 Dec 2021

Project Type

GRANT

Keywords

Mycobacterium tuberculosis-Mycobacteria;Vaccine Development;Immunology;Infectious Disease Control

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

741092

Project Team

N/A