Biodiscovery from Wet Tropics' native plants (Old ID 27532)
Role
Principal Investigator
Description
Inflammatory bowel disease (IBD) affects 1 in 250 Australians including the people living in the FNQ region. It cost Australians a total of $3.18 billion per annum. Given that it has no cure and the disease prevalence and its associated cost are expected to increase sharply, there is an urgent need for new drugs. Inspired by the Wet Tropics' biodiversity of Far North Queensland (FNQ), the proposed project envisions discovering novel anti-inflammatory drug leads for IBD from selected climate-affected native plants using cutting-edge drug discovery techniques and technologies. The aims are : • Determine the metabolomes of the anti-inflammatory extracts of five native mountaintop plants using mass spectrometry techniques. • Isolate anti-inflammatory molecules from Uromyrtus metrosideros extract using chromatographic techniques.
Date
01 Mar 2022 - 01 Sep 2024
Project Type
GRANT
Keywords
Wet Tropics;Biodiscovery;Inflammatory Bowel Disease;Anti-inflammatory drug lead;Natural Products;Climate change
Funding Body
Far North Queensland Hospital Foundation
Amount
5000
Project Team
Karma Yeshi