Development of disulfide-rich peptides for drug design (Old ID 19353)
Role
Principal Investigator
Description
Peptides are an outstanding source of potential drug candidates for therapeutic applications because of their potency and specificity for a range of different drug targets. However, the inherent poor stability of peptides limits their application. This project seeks to overcome this limitation by using tightly folded scaffolds, such as those found in the venom of spiders and scorpions, to improve stability. It is anticipated that these studies will significantly expand the potential of peptides as therapeutics. In particular, peptide-based drug leads for cancer and autoimmune diseases will be explored because of the enormous impact they have on health care in Australia and the urgent need for more effective treatments.
Date
01 Mar 2012 - 31 Dec 2016
Project Type
FELLOWSHIP
Keywords
peptidesw;Structural Biology;Cancer
Funding Body
Australian Research Council
Amount
714528
Project Team
N/A