The ecological and evolutionary factors influencing the establishment and persistence of community associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in resourcelimited, high-burden settings (Old ID 27344)
Role
Principal Investigator
Description
Our preliminary data suggests that there is high circulation of methicillin resistant Staphylococcus aureus (CA-MRSA) in the highlands of PNG. We propose a hospital- and community-based study to determine the ecological and evolutionary factors associated with the establishment of the highly virulent MRSA ST93 clone in the highlands of PNG. This study will provide vital information for clinicians, public health professionals and policy makers in PNG to guide treatment and interventions to reduce the impact of MRSA-associated AHO in the country. Indeed, these findings will also inform strategies for the treatment and prevention of MRSA-associated AHO in other resource-limited settings.
Date
01 Jan 2022 - 31 Dec 2025
Project Type
GRANT
Keywords
Staphylococcus Aureus;MRSA;Osteoarthritis;Papua New Guinea;Zoonosis;Genomics
Funding Body
National Health and Medical Research Council (NHMRC)
Amount
603908
Project Team
Eike Steinig;Cadhla Firth