Mecaflavo - Understanding the Anti-inflammatory Structure-Activity Relationships of Flavonoid Analogues [Compréhension des relations structures-activités dans les MECanismes Anti-inflammatoires d’analogues de FLAVOnoïdes] – MECAFLAVO (Old ID 27204)
Ministry of Foreign Affairs and International Development (MAEDI)
Role
Principal Investigator
Description
Flavonoids are a class of natural compounds with various phenolic structures that are widely distributed in plants, including fruits and vegetables, tea or wine. The project MECAFLAVO will synthesize and evaluate the anti-inflammatory potential of pinocembrin and pinobanksin analogues in order to understand their mechanism of action, metabolism and therapeutic safety. Through derivatization it further aims to improve the therapeutic profile and applications of these semi-synthetic compounds.
Date
01 Jul 2021 - 31 Dec 2023
Project Type
GRANT
Keywords
flavonoids;anti-inflammatories;natural products;green chemistry;medicinal chemistry;tropical health
Funding Body
Ministry of Foreign Affairs and International Development (MAEDI)
Amount
2996
Project Team
Jayson Wau;Tyler Goodine