PHTM - Tropical Health


Patricia Graves

Patricia Graves

Dave Sellars

Dave Sellars

Richard Bradbury

Richard Bradbury

Ending the neglect – setting the platform for strongyloidiasis elimination in Australia
Richard Bradbury
01 Jan 2024 - 31 Dec 2028
Strongyloidiasis is caused by parasitic nematodes (roundworms) of the genus Strongyloides and is considered to be one of the most neglected of the neglected tropical diseases (NTDs). There are two main Strongyloides species that cause human infection; S. stercoralis and S. fuelleborni. In Australia, S. stercoralis is the infecting species that disproportionately affects remote Indigenous communities, with the prevalence ranging from 10-60%. The lifecycle and transmission is complex with both a parasitic cycle and a free-living cycle. This is further complicated by autoinfection and the possibility of zoonotic transmission– recent genetic evidence suggests the possibility of a dog reservoir. These factors coupled with less than ideal diagnostics and treatment options (Ivermectin and Albendazole) where there is evidence of treatment failures, the spectre of emerging resistance and their inability to prevent reinfection, all have implications for control and elimination efforts. It is our central thesis that strongyloidiasis is a zoonotic neglected tropical disease of public health importance in Australia and that an integrated interdisciplinary “One Health” approach is required for its elimination.
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2025
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2018
End Date: 01 Jan 2022
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2010
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2012
Start Date: 01 Jan 2012
Start Date: 01 Jan 2012
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2014
Reseracher: Thu Nguyen (Research Fellow)
Start Date: 01 Jan 2018
Start Date: 01 Jan 2020
Start Date: 01 Jan 2021