Research & Innovation Services

Paul Giacomin

Research Development and Partnership Advisor
paul.giacomin@jcu.edu.au

Arnold Mangott

Research Development and Partnership Advisor
arnold.mangott@jcu.edu.au

Exploring new therapeutic approaches for coeliac disease based on biological effects of hookworm treatment. (Old ID 27271)

Paul Giacomin

01 May 2021 - 30 Nov 2022

We hypothesise that hookworm infection creates an anti-inflammatory environment in the small intesti...

Novel therapeutics for diabetes sourced from Northern Australian biota. (Old ID 27346)

Paul Giacomin

02 Aug 2021 - 30 Jun 2023

he aim of this project is to develop lead diabetes drug candidates from hookworm saliva and build a ...

Laser based diagnostics for STH infections (Old ID 26822)

Paul Giacomin

01 Jan 2020 - 30 Apr 2022

Developing novel laser based methods for rapid diagnosis and quantification of parasitic worm infect...

Can experimental hookworm infection prevent metabolic disease/Type 2 diabetes? (Old ID 24710)

Paul Giacomin

01 Jan 2018 - 01 Jun 2019

We will conduct a world-first clinical trial in Cairns testing the safety and efficacy of experiment...

New therapies for Coeliac Disease: Helminths and their secreted products. (Old ID 22524)

Paul Giacomin

01 Feb 2016 - 01 May 2019

Coeliac Disease (CeD) is a common and debilitating autoimmune disorder (affecting 1% of the Queensla...

Hookworm peptide therapeutic for oral treatment of IBD (Old ID 26317)

Paul Giacomin

01 Jan 2020 - 30 Jun 2022

We intend to develop an orally delivered peptide that can modulate the immune system and be develope...

Novel therapeutics for diabetes sourced from Northern Australian biota. (Old ID 27321)

Paul Giacomin

01 Jul 2021 - 30 Jun 2022

The aim of this project is to develop lead diabetes drug candidates from hookworm saliva and build a...

Hookworm therapy for restoring tolerance in coeliac disease (Old ID 22142)

Paul Giacomin

01 Oct 2016 - 30 Mar 2018

Parasitic worms have an amazing ability to manipulate the immune system, and our research group rece...

Hookworm therapy for Coeliac Disease: A randomised, double blink, placebo-controlled clinical trial (Old ID 22151)

Paul Giacomin

01 Jan 2016 - 30 Apr 2021

Parasitic worms have an amazing ability to manipulate the immune system, and our research group rece...

Preclinical evaluation of novel drug lead compounds discovered from Wet Tropics plant (Old ID 28949)

Paul Giacomin

01 Jan 2023 - 15 Sep 2025

Inflammatory bowel disease (IBD) affects 1 in 250 Australians including the people living in Far Nor...

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease

2015
Elsevier
Researchers:Paul Giacomin

Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling

2015
Oxford University Press
Researchers:Paul Giacomin

Comparison of astaxanthin accumulation and biosynthesis gene expression of three Haematococcus pluvialis strains upon salinity stress

2015
Springer
Researchers:Arnold Mangott

Nutritional evaluation of Australian microalgae as potential human health supplements

2015
Public Library of Science
Researchers:Arnold Mangott

Does Strongyloides stercoralis infection protect against type 2 diabetes in humans? Evidence from Australian Aboriginal adults

2015
Elsevier
Researchers:Paul Giacomin

Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects

2015
Nature Publishing Group
Researchers:Paul Giacomin

Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity

2015
The Rockefeller University Press
Researchers:Paul Giacomin

Suppression of inflammation by helminths: a role for the gut microbiota

2015
Royal Society
Researchers:Paul Giacomin

Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia

2015
PLOS
Researchers:Paul GiacominJonathan Golledge