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Shiv Thanigaimani

Projects

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Publications

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Awards

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Biography

Biography:

I was trained in biotechnology at Flinders University and received PhD in Medicine from the University of Adelaide after completing a research program investigating reverse atrial remodeling in a hypertensive large animal model. I continued to explore the prevention of atrial remodeling with small animal models during my work as a postdoctoral fellow. Later, I joined as a postdoctoral research scientist at the Queensland Research Centre for Peripheral Artery Diseases. In 2023, I was promoted as Research fellow (Peripheral vascular disease).

Research:

My broad research interests span within vascular biology, specifically in understanding the risk factors and mechanisms of peripheral artery diseases. I primarily perform pre-clinical and in vitro studies involving development of PAD animal models via microsurgery, tissue culture and a number of molecular biology techniques. Clinically, I am involved in determining risk factors of PAD through various statistical techniques using prospectively collected patient data. My research aim is to enable direct translation of my work towards improving patient management.

I would welcome any inquiries from students interested in gaining research experience or undertaking honors or PhD research projects in topics including abdominal aortic aneurysm, limb ischemia and limb ulcers.

Scientific contribution:

International advisory board member - CIMSER, Loyola college, India.

Grant reviewer - Diabetes Australia.

Editorial board member - BMC cardiovascular disorders, BMC research notes, Cardiovascular therapeutics.

Review editor - Frontiers (General Cardiovascular Medicine, Atherosclerosis and Vascular Medicine, Aortic surgery and endovascular repair).

Peer reviewer - European Journal of Pharmacology, International Journal of Medical Sciences (IJMS), Cells, Journal of Clinical Medicine (JCM), Current Molecular Medicine (CMM), Current Vascular Pharmacology (CVP) and Molecules.

Teaching

Current JCU Research Students
Investigating a novel potential therapy for abdominal aortic aneurysm
Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
Evaluation of the Effect of a Direct 5' Adenosine Monophosphate-activated Protein (AMP) Kinase(AMPK) Activator in Inhibiting Abdominal Aortic Aneurysms (AAA) in Mouse Model
Doctor of Philosophy (Health)
Role of myokines induced by peripheral ischemia in regulating aortic phenotypic modifications and limiting abdominal aortic aneurysm progression.
Doctor of Philosophy (Medical, Molecular and Veterinary Sciences)
The role of KCa and KATP channels in regulating vascular tone and aortic wall stability/ integrity in AAA pathogenesis.
Doctor of Philosophy (Health)
Developing a Risk Score to predict the Risk of Major Adverse Cardiovascular events in Patients with Abdominal Aortic Aneurysm
Master of Philosophy (Health)
Completed Honours and External Research Students
Comparing outcomes of peripheral revascularisation in Aboriginal and/or Torres Strait Islander patients to non-Indigenous patients with intermittent claudication
HONOURS