Tropical diseases: Translating discoveries into better health (Old ID 24683)

National Health and Medical Research Council (NHMRC)
Role

Principal Investigator

Description

Our overall working hypotheses are: 1. The rational design of tropical disease vaccines and other therapeutics requires improved understanding of immunology, host-parasite interactions and application of innovative bioengineering. 2.Improved interventions will be required to eliminate tropical infectious diseases. Our Specific Aims are: 1. Discover pathogenic and immune mechanisms, protective antigens, biomarkers and therapeutic targets for the control of tropical infectious diseases. 2. Develop new vaccines, therapeutics and diagnostics. 3. Optimise human pathogen challenge models to study host-pathogen interactions and test new vaccines and therapeutics. 4. Develop and test new clinical and public health interventions in disease-endemic settings.

Date

01 Jan 2018 - 31 Dec 2022

Project Type

GRANT

Keywords

Malaria;Vaccine;Diagnostic;Protein;Therapeutic;Immunomodulatory

Funding Body

National Health and Medical Research Council (NHMRC)

Amount

4400810

Project Team

Alex Loukas